Kidney disease results from damage to the nephrons, which are the tiny structures inside your kidneys that filter blood.
Chronic Kidney Disease (CKD) develops when the kidneys lose most of their ability to remove waste and maintain fluid and chemical balances in the body. CKD can progress quickly or take many years to develop.
Risk Factors Include:
Many times, kidney disease cannot be cured; however, it can be managed. Taking certain steps during the early stages of the disease will help keep the kidneys healthy longer.
Since kidney disease sometimes has no symptoms, doctors may first detect the condition through routine blood and urine tests. The National Kidney Foundation recommends three simple tests to screen for kidney disease: a blood pressure measurement, checking for extra protein in your blood or urine, and measuring how well your kidneys are filtering wastes from your blood (Glomerular Filtration Rate or GFR).
High blood pressure (HBP), also known as Hypertension, can lead to kidney disease. It can also be a sign that your kidneys are already impaired. The only way to check blood pressure is to have a health professional measure with a blood pressure cuff. The result is expressed as two numbers. The top number, (called the systolic pressure) represents the pressure as the heart beats. The bottom number, (called the diastolic pressure) shows the pressure when the heart is resting. Your blood pressure is considered normal if it stays below 120/80 (expressed as "120 over 80").
Healthy kidneys take wastes out of the blood but leave protein. Impaired kidneys may fail to separate a blood protein called albumin from the wastes. At first, small amounts of albumin leak into the urine, a condition known as microalbuminuria. As kidney function worsens, the amount of albumin and other proteins in the urine increases, and the condition is called proteinuria. Doctors test for protein using a dipstick in a small sample of urine taken in the doctor's office. The color of the dipstick indicates whether or not there is protein the urine.
A more sensitive test for protein or albumin in the urine involves testing a blood sample for the amount of protein and a waste product called creatinine. Creatinine is a waste created every time you use your muscles. When the kidneys aren't working well, the level of creatinine in your blood goes up. This test is used to detect kidney disease in people at high risk, especially those with diabetes.
This test is also known as "measuring the Glomerular Filtration Rate (GFR)." The (GFR) is a measure of how well the kidneys filter wastes from the blood. GFR is been estimated from a routine measurement of creatinine in your blood. By comparing GFR tests done at different times, a doctor knows whether kidney function is getting better or worse.
Sources:
National Kidney Disease Education Program (NKDEP)
National Institutes for Diabetes & Digestive & Kidney Diseases