Philip J. Klemmer, MD
Professor of Medicine

Email: philip_klemmer@med.unc.edu
Phone: (919) 966-2561 x 257
Fax: (919) 966-4251
Office Location: 7016 Burnett-Womack

Specialty Areas: Clinical Nephrology

Chronology:
BA: Gettysburg College, 1968; MD: Temple University, 1972; Resident: University of North Carolina, 1972-3; Junior Assistant Resident: University of North Carolina, 1973-4; Senior Assistant Resident: University of North Carolina, 1974-5; Nephrology Fellow: University of North Carolina, 1975-7; Assistant Professor of Medicine: University of North Carolina, 1977-80; Private Practice Nephrologist: Winchester Medical Consultants, 1980-1998; Co-Director: Winchester Dialysis Center, 1980-1998; Professor of Medicine: University of North Carolina, 1998-Present

Dr. Klemmer is primarily interested in clinical nephrology, particularly metabolic bone disease, disorders of divalent ion metabolism, and their relationship to vascular calcification. Other interests include renal dysfunction in hepatic disease, inherited interstitial renal disease - including Gitelman's syndrome and medullary cystic renal disease - environmental renal disease and the mechanisms by which tobacco promotes atherosclerosis. Dr. Klemmer teaches about mechanisms of hypertension development, integrates whole organ and whole body physiology with more recent genetic and molecular biological discoveries. His clinical interests extend to outpatient dialysis and improving patient outcomes.

Selected Bibliography:

Bomback AS, Kshirsagar AV, Ferris ME, Klemmer PJ. J Renin Angiotensin Aldosterone Syst. 2009 Dec;10(4):230-6. Epub 2009 Oct 28.

Bomback AS, Katz R, He K, Shoham DA, Burke GL, Klemmer PJ. Sugar-sweetened beverage consumption and the progression of chronic kidney disease in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr. 2009 Nov;90(5):1172-8. Epub 2009 Sep 9.

Bomback AS, Klemmer PJ. Interaction of aldosterone and extracellular volume in the pathogenesis of obesity-associated kidney disease: a narrative review.
Am J Nephrol. 2009;30(2):140-6. Epub 2009 Mar 20. Review.

Klemmer PJ, Bomback AS. Extracellular volume and aldosterone interaction in chronic kidney disease. Blood Purif. 2009;27(1):92-8. Epub 2009 Jan 23. Review.

Kshirsagar AV, Craig RG, Moss KL, Beck JD, Offenbacher S, Kotanko P, Klemmer PJ, Yoshino M, Levin NW, Yip JK, Almas K, Lupovici EM, Usvyat LA, Falk RJ. Periodontal disease adversely affects the survival of patients with end-stage renal disease. Kidney Int. 2009 Apr;75(7):746-51. Epub 2009 Jan 21.

Kshirsagar AV, Bang H, Bomback AS, Vupputuri S, Shoham DA, Kern LM, Klemmer PJ, Mazumdar M, August PA. A simple algorithm to predict incident kidney disease. Arch Intern Med. 2008 Dec 8;168(22):2466-73.

Bomback AS, Kshirsagar AV, Klemmer PJ. Renal aspirin: will all patients with chronic kidney disease one day take spironolactone? Nat Clin Pract Nephrol. 2009 Feb;5(2):74-5. Epub 2008 Nov 25.

Anderson JJB and Klemmer PJ Phosphorus (chapter) In: Present Knowledge in Nutrition, 9th Ed ILSI Press, Washington DC Editors: Bowman BA and Russell RM 2005.

Wong LP, Blackley MP, Andreoni KA, Chin H, Falk RJ, Klemmer PJ. Survival of liver transplant candidates with acute renal failure receiving renal replacement therapy. Kidney Int. 2005 Jul;68(1):362-70.

Kiser RL, Wolf MT, Martin JL, Zalewski I, Attanasio M, Hildebrandt F, Klemmer P. Medullary cystic kidney disease type 1 in a large Native-American kindred. Am J Kidney Dis. 2004 Oct;44(4):611-7.

Klemmer PJ. Calcium loading, calcium accumulation, and associated cardiovascular risks in dialysis patients. Blood Purif. 2005;23 Suppl 1:12-9. Review.

Kiser RL, Wolf MT, Martin JL, Zalewski I, Attanasio M, Hildebrandt F, Klemmer P. Medullary cystic kidney disease type 1 in a large Native-American kindred. Am J Kidney Dis. 2004 Oct;44(4):611-7.

Klemmer PJ, Chalermskulrat W, Reif MS, Hogan SL, Henke DC, Falk RJ. Plasmapheresis therapy for diffuse alveolar hemorrhage in patients with small-vessel vasculitis. Am J Kidney Dis. 2003 Dec;42(6):1149-53.

Kiser RL, Thomas DB, Andreoni K, Klemmer PJ. Preexisting crescentic glomerulonephritis in the renal allograft. Am J Kidney Dis. 2003 Nov;42(5):E20-6.

Click here for a list of publications on PubMed.

 

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